Mgr. Miroslav Micka, Ph.D.

2025

• A class III ligand oscillates between internal and terminal binding modes as it engages with the Dishevelled PDZ domain

  KUMAR Jitender MICKA Miroslav KOMÁREK Jan KLUMPLER Tomáš BYSTRÝ Vojtěch SPRANGERS Remco BARINKA Cyril BRYJA Vítězslav TRIPSIANES Konstantinos

  Article in Periodical

  Structure, year: 2025, volume: 33, edition: 8, DOI

2024

• Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein

  KRAVEC Marek ŠEDO Ondrej NEDVEDOVA Jana MICKA Miroslav ŠULCOVÁ Marie ZEZULA Nikodém GÖMÖRYOVÁ Kristína POTĚŠIL David GANJI Sri Ranjani BOLOGNA Sara ČERVENKA Igor ZDRÁHAL Zbyněk HARNOŠ Jakub TRIPSIANES Konstantinos JANKE Carsten BARINKA Cyril BRYJA Vítězslav

  Article in Periodical

  EMBO Journal, year: 2024, volume: 43, edition: 22, DOI

2021

• Can We Pharmacologically Target Dishevelled: The Key Signal Transducer in the Wnt Pathways?

  MICKA Miroslav BRYJA Vítězslav

  Chapter of a book

  Pharmacology of the WNT Signaling System, year: 2021, number of pages: 19 s.

2019

• Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

  HANÁKOVÁ Kateřina BERNATÍK Ondřej KRAVEC Marek MICKA Miroslav KUMAR Jitender HARNOŠ Jakub OVESNÁ Petra PACLÍKOVÁ Petra RÁDSETOULAL Matěj POTĚŠIL David TRIPSIANES Konstantinos ČAJÁNEK Lukáš ZDRÁHAL Zbyněk BRYJA Vítězslav

  Article in Periodical

  Cell Communication and Signaling, year: 2019, volume: 17, edition: 1, DOI