Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 137
2026
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Psychrotolerant Erwinia psychrophila sp. nov. and Erwinia magellanica sp. nov. Isolated from Penguin Faeces
CURRENT MICROBIOLOGY, year: 2026, volume: 83, edition: 2, DOI
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Triazinyl-benzenesulfonamide derivatives as hCA IX inhibitors: Design, synthesis, and activity determination using an optimized stop-flow methodology
BIOORGANIC CHEMISTRY, year: 2026, volume: 170, edition: March, DOI
2025
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: From Single Molecules to Tissues: Correlative BioAFM Serving as Core Facility
Year: 2025, type: Conference abstract
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3rd ML4NGP Training School "NMR for Intrinsically Disordered Proteins (IDPs)"
Year: 2025, type: Workshop
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AFM application across the life sciences field and its combination with special techniques
Year: 2025, type: Conference abstract
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Arg-C Ultra Simplifies Histone Preparation for LC-MS/MS
Analytical chemistry, year: 2025, volume: 97, edition: 24, DOI
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Bacterial lectins in complex bacterium-nematode-insect tripartite system
Year: 2025, type: Conference abstract
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Bio-SAXS Practical Course 2025
Year: 2025, type: Workshop
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Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system
iScience, year: 2025, volume: 28, edition: 9, DOI
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CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3
Open Biology, year: 2025, volume: 15, edition: 1, DOI