Animal physiology, immunology and developmental biology

Doctoral degree in full-time or combined form. The language of instruction is Czech.

The programme can be studied only as a single subject.

Application deadline depending on the admission procedure chosen (midnight 30 April 2026 or 15 December 2026)

What will you learn?

The aim of the program is to prepare top specialists in specific scientific fields developed within the Department of Animal Physiology and Immunology at the Institute of Experimental Biology, Faculty of Science, Masaryk University. Graduates are prepared for further scientific careers at workplaces of basic or applied research at the international level, but also for possible employment in companies with a research background, in medical facilities and as professional lecturers.

The program focuses on the research formation of students in the rapidly developing fields of physiology, immunology and developmental biology. Students are trained to conduct research in the areas ranging from cellular to organ level to models of whole animal organisms from cells to humans. Modern molecular biology techniques and state-of-the-art imaging techniques are applied. The program covers research topics ranging from veterinary through biomedical applications to general basic research issues. In particular, the most represented topic is the research of cellular signaling, which is crucial for understanding the processes controlling embryonic development, tissue differentiation and regeneration, as well as processes of carcinogenesis or immune regulation. The program integrates methodological approaches of molecular biology, molecular embryology and cell biology with morphological and behavioral approaches.

The course is designed to motivate prospective students through checkpoints. A greater number of methodologically oriented courses, internships, and openness to contacts with biotechnology companies ensure interconnection with the practice of modern biological research. Emphasis is placed on using English as a basic tool for scientific work.

Students are motivated by the high professional quality of research in an open and friendly environment. The performance of individual students is appreciated both financially and, for example, through participation in prestigious international conferences.

Practical training

The program includes compulsory student practice at potential employers as a tool for establishing links with future employers.

Further information

The Office for Doctoral Studies, Quality, Academic Affairs and Internationalization takes care of doctoral students SCI MU

https://www.sci.muni.cz/en/students/phd

On the department's website, you can find the following information:

  • Forms (application forms for state examinations and defences, various applications, etc. )
  • Legislation (links to: MU Study and Examination Regulations, Scholarship Regulations of MU, Terms of Scholarship Programmes of the Faculty of Science)
  • Dissertations (Guidelines for dissertations, templates)
  • Manuals (guidelines for Individual Study Plans, study and research obligations in DSP, etc.)
  • Doctoral study programmes (recommended study plans, examination committees, overview of accredited programmes)
  • Deadlines for the doctoral state examinations and defences
  • Enrolment (information needed for the enrolment to the next semester)
  • Graduation

but also office hours, contacts, news, information on skills development and scholarships.

Detailed information on stays abroad can be found on this website:

https://www.sci.muni.cz/en/students/phd/develop-your-skills/stay-abroad

Career opportunities

The program is designed to be comparable with high-quality foreign universities programmes and graduates work well at top research institutes, whether from academic or non-academic institutions. The director of the Academy of Sciences of the Czech Republic, Key Manager of Roche Diagnostics, Postdoc at the Karolinska Institutet or the director of the embryological laboratory are examples of positions where our graduates found employment and refer for the program. Graduates of the doctoral study program are therefore entitled to carry out independent scientific and research activities in the field of basic and applied research, but they are also employed in management positions thanks to their language and managerial competencies. In a broader sense, they are prepared to carry out all activities related to scientific work; to deal with conceptual issues, scientific-organizational activities and teaching.

Admission requirements

Admission to Doctoral degree programmes in 2026/2027 (beginning: Autumn 2026)
— Submission deadline until midnight 30 Apr 2026

Admission procedure
Admission board checks the candidates' professional capacities in an entrance interview that is conducted in English. The candidates submit a structured CV and in the course of the interview, they will present a brief proposal of their PhD project, will define the anticipated outputs, and suggest a methodical procedure. Written plan of candidate's suggested research project is also mandatory and will be submitted to the board. Recommended length of the plan is two pages and the structure is as follows: Title, Name of applicant, Name of supervisor, Home institution, Synopsis, Aims, Methodology, Financial covering. In a discussion with the admission board and in the presence of their supervisor they have to demonstrate that their respective thesis topic is scientifically well-grounded and experimentally manageable. A necessary prerequisite for admission is a demonstrable capability of professional conversation in English. The sufficient financial coverage of the candidate's scientific project will be assessed by the admission board within the terms of the entrance interview and further within the terms of the PhD Workshop in the 3rd semester.
The admission board assesses the candidates’ knowledge and prerequisites for the independent scientific work (0-200 points) and the capability of communication in English (0-100 points).

Date of the entrance exam
The applicants will receive information about the entrance exam by e-mail usually at least 7 days before the exam.
Please, always check your e-mails, including spam folders.

Conditions of admission
To be admitted, the candidate must obtain at least 120 points in the professional and at least 60 points in the language part of the interview.
Successful applicants are informed of their acceptance by e-mail and subsequently receive an invitation to the enrolment.

Programme capacity
The capacity of a given programme is not fixed; students are admitted based on a decision by the Doctoral Board after assessing their aptitude for study and motivation.

International applicants for doctoral study (Czech and Slovak Republics applicants NOT included)
— Submission deadline until midnight 15 Dec 2026

Admission procedure
Admission board checks the candidates' professional capacities in an entrance interview that is conducted in English. The candidates submit a structured CV and in the course of the interview, they will present a brief proposal of their PhD project, will define the anticipated outputs, and suggest a methodical procedure. Written plan of candidate's suggested research project is also mandatory and will be submitted to the board. Recommended length of the plan is two pages and the structure is as follows: Title, Name of applicant, Name of supervisor, Home institution, Synopsis, Aims, Methodology, Financial covering. In a discussion with the admission board and in the presence of their supervisor they have to demonstrate that their respective thesis topic is scientifically well-grounded and experimentally manageable. A necessary prerequisite for admission is a demonstrable capability of professional conversation in English. The sufficient financial coverage of the candidate's scientific project will be assessed by the admission board within the terms of the entrance interview and further within the terms of the PhD Workshop in the 3rd semester.
The admission board assesses the candidates’ knowledge and prerequisites for the independent scientific work (0-200 points) and the capability of communication in English (0-100 points).

More information about admission process for international applicants in general can be found in the section Admission Process.

Date of the entrance exam
The applicants will receive information about the entrance exam by e-mail usually at least 10 days before the exam.
Please, always check your e-mails, including spam folders.

Conditions of admission
To be admitted, the candidate must obtain at least 120 points in the professional and at least 60 points in the language part of the interview.
Successful applicants are informed of their acceptance by e-mail and subsequently receive an invitation to the enrolment.

Programme capacity
The capacity of a given programme is not fixed; students are admitted based on a decision by the Doctoral Board after assessing their aptitude for study and motivation.

Deadlines

1 Jan – 30 Apr 2026

Submit your application during this period

Admission to Doctoral degree programmes in 2026/2027 (beginning: Autumn 2026)

2 Jan – 15 Dec 2026

Submit your application during this period

International applicants for doctoral study (Czech and Slovak Republics applicants NOT included)

Dissertation topics

Single-subject studies

Pathophysiology of Sprouty proteins and their association with ciliopathies
Supervisor: prof. RNDr. Marcela Buchtová, Ph.D.

Sprouty proteiny představují kontrolní mechanismus signalingu aktivovaných tyrosinkinázových receptorů, včetně FGF signální dráhy. U myší způsobuje delece Sprouty vývojové poruchy vedoucí k poškození sluchu, kraniofaciálním defektům, zpomalenému postnatálnímu růstu nebo jícnové achalázii a střevní pseudoobstrukci. Význam lidského genu Sprouty2 byl zaznamenán u nefropatie, thanatoforické dysplázie a v různých typech onkologických onemocnění. V poslední době se ukazuje, že syndromy podmíněné hyperaktivací signální dráhy růstových fibroblastových faktorů (FGF) a syndromy spojené s deregulovanou funkcí primárních cilií se projevují řadou společných fenotypů, kromě jiných také u kraniofaciálních a achondroplastických malformací. PhD projekt se zaměří na charakterizaci role Sprouty proteinů v průběhu skeletogeneze, vyhodnotíme vývojové defekty tkání a orgánů myšího modelu s deletovaným Sprouty2 a Sprouty 4, které se běžně vyskytují u ciliopatií a zanalyzujeme signální dráhy modulované primárními ciliemi v morfogenezi Sprouty deficientních myší.

Supervisor

prof. RNDr. Marcela Buchtová, Ph.D.

Study information

Provided by Faculty of Science
Type of studies Doctoral
Mode full-time Yes
combined Yes
distance No
Study options single-subject studies Yes
single-subject studies with specialization No
major/minor studies No
Standard length of studies 4 years
Language of instruction Czech
Collaborating institutions
  • The Czech Academy of Sciences
  • Biofyzikální ústav AV ČR
  • Ústav biologie obratlovců AV ČR
Doctoral board and doctoral committees

Do you have any questions?
Send us an e-mail to

prof. Mgr. Vítězslav Bryja, Ph.D.

Consultant

e‑mail:

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