NMR studie přirozeně neuspořádaných proteinů. Structurní studie bakteriální RNA polymerázy a jejích podjednotek. Studie Microtubule associated protein 2c a jeho vazby na mikrotubuly.
Akademické stáže, studijní nebo pracovní pobyty
16. 6. 2025 – 15. 7. 2025: Institute of Structural Biology, Grenoble, Ostatní, FRA
The purpose of this stay is to learn to use the ABSURD software, which allows us to combine molecular dynamics simulations with Nuclear Magnetic Resonance Relaxation data. This is essential for simulations in intrinsically disordered proteins. This software was developed by the research group of Martin Blackledge in Grenoble.
The purpose of this stay is to learn advanced methods for analysis of flexible proteins using experimental SAXS and NMR(chemical shifts, PRE, RDC) data. This includes the ASTEROIDS algorithm and other tools developed by the research group of Martin Blackledge in Grenoble.