Mgr. Helena Peschelová, Ph.D.

2025

• Adenosine (de)methylation on the crossroads of RNA and DNA synthesis

  KRISHNA Shwetha OBRDLÍK Aleš RENGARAJ Praveenkumar ŠEMBEROVÁ RÁJECKÁ Veronika ZUEV Anton PESCHELOVÁ Helena KOZLOVÁ Veronika ŠMÍDA Michal POTĚŠIL David DOBROVOLNÁ Jana VAŇÁČOVÁ Štěpánka

  Conference abstract

  Year: 2025, type: Conference abstract

• FTO m6A RNA demethylase is important for proper DNA replication in human cells, TALK, Heidelberg, The epitranscriptome

  KRISHNA Shwetha OBRDLÍK Aleš ZUEV Anton RENGARAJ Praveenkumar ZLOBINA Maria PESCHELOVÁ Helena KOZLOVÁ Veronika ŠMÍDA Michal DOBROVOLNÁ Jana VAŇÁČOVÁ Štěpánka

  Conference abstract

  Year: 2025, type: Conference abstract

2024

• EXPLORING VENETOCLAX RESISTANCE MECHANISMS IN AML CELLS THROUGH GENOME-WIDE CRISPR SCREENS AND DRUG PROFILING

  LADUNGOVÁ Adriana STYLIANOU Filio PESCHELOVÁ Helena LODHI Yusuf DOSTÁLOVÁ Lenka GOTTUMUKKALA Narendra Varma ŠMÍDA Michal

  Conference abstract

  Year: 2024, type: Conference abstract

2023

• CRISPR/Cas9 technology as a useful tool in the study of chornic lymphocytic leukemia.

  PESCHELOVÁ Helena MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• CRISPR/Cas9 technology as a useful tool in the study of chronic lymphocytic leukemia.

  PESCHELOVÁ Helena KOZLOVÁ Veronika MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Exploring the mechanisms of Venetoclax resistence via drug screening and genome-wide CRISPR screening.

  LADUNGOVÁ Adriana PESCHELOVÁ Helena DOSTÁLOVÁ Lenka LODHI Yusuf GOTTUMUKKALA Narendra Varma MAYER Jiří ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Genome-wide CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation in rituximab-resistant cells.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Genome-wide CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Identification of novel targets that upregulate CD20 expression in rituximab-resistant cells with the use of genomewide CRISPR screening.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

2022

• CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2022, type: Conference abstract